Hi, author of the Big Factories mod here.
When I run Bob's Technology, Big Factories and DiscoScience together in one game, it causes the Big Bob's lab added by Big Factories to have a way too big sprite. I think it's because both your mod and mine change the sprite defined by Bob. I did some testing, and allowing my mod to load before yours, will solve the issue. Could you add my mod as an optional dependency, so the game knows to load mine first?
My other option is to add an incompatibility with DiscoScience, but I'd rather not do that since it works fine without Bob's.
I'm not great with graphics, so if you have a better idea to solve this, I'm open to that too.
For details, see https://mods.factorio.com/mod/big-factories/discussion/5d398b300f01ac002dca864f