I have both of those running in that save, I'm running a pretty long list of mods though, its possible something broke or an incompatibility popped up inbetween shuffling things around but its been happening inbetween generating a few different worlds without changing things inbetween then, and inconsistently too. If you give me some time I can put forward some more direct information with what I seem to have been experiencing, but alien biomes and dectorio i have not disabled between saves, this has been occurring even on freshly generated worlds, perhaps i could upload a save or something somewhere if itll help. With Alien Biomes I do have obsolete tiles disabled though (to use modmash splinter undergroung + subways, but it still occurs without that mod) and i imagine that tick number is tied to the "creep spread factor".