Companion Drones seem to conflict when using the Editor Extensions mod. Specifically switching to editor mode. They will start attacking your buildings while you are away. I suspect it's that your or their faction changes and it throws them for a loop.
Was a bit funny, as the testing lab mode includes a warning about time still flowing for your factory and to make sure it still exists. Imagine my surprise when I switch back and I get a warning that my factory is under attack. I initially think "oh, the companions took them out. That was fast." I switch and then switch back, and they immediately go and blow up a radar!