I run four servers all hosting my mod Brave New Oarc - which supports Space Block. But we usually can only run a few days since Space Block consumes more memory than any other mod (Krastorio, Freight Forward, SeaBlock, Alien modules, or normal Fractorio) all running with Brave new oarc.
I suspect the issue is the background that is randomly placed around the map. Do you have any insight. I could run some tests to see if it can be improved. I have a high memory save if you want to look. I know the tools don't really let us query the memory usages.
If you want to see our server - search Maroons. I appreciate any help you can provide on this in finding the high memory usage areas of mods.