As far as I can tell by comparing this to the 4.1 (spiwn) and 4.2 (Shadoxa) versions of the mod, there's no reason to mark SE and K2 as required dependencies; using optional dependencies instead would work just fine.
Especially after adding a dependency on DSR, it would be nice if non-SE/K2 players could benefit from that fix.
The marking was for purposes to confirm that this version works with these mods, as there was a timeframe when no other mods supported the combination (due to updates in those mods)