When using the hotkey, items on the cursor can be deleted. I just lost a bunch of modules trying to insert them into machines! (the keybind conflict could be another feedback post)
To recreate:
Remove any blueprints from the inventory. Error does not occur if there's an existing Recipe as Combinator blueprint.
Hold an item on the cursor.
Press the hotkey (ctrl-D) over a machine
Item on cursor is removed.