As is, the mod works pretty great, but there's one issue....if you disable the mod in order to play vanilla and forget to re-sync mods and return to save, it kinda messes up generator....However, if you add at least one item, or a research to your mod, this will result in a popup message informing the user of migrated content. This should let them know that they should close the game without saving and re-sync mods [as they should of done anyways]. This sorta act as kinda a dirty but simple way of letting the user know that they are dumb and forgot to re-enable your mod by using the migrated-content popup that appears when you load a world without a mod previously enabled.

simplest solution i can think of for this is to create a very cheap piece of research. Call it whatever. Add it as a pre-requisite to some of the early science so that a player has to research it at the beginning of their island. then if they accidentally remove the mod, it results in the migrated-content popup.