I figured out why this happens while trying to update to IR 3.1. IR adds a new force for the Manifesto simulations and researches all techs for this force. Warptorio does some weird abstraction causing it to not handle resets or multiple forces properly.
I don't know if it's possible to fix without forking Warptorio because the remote interfaces are not documented. Anyways, consider it a gift to make this mod a bit easier :)