100% bonus does not preserve the mostly-vanilla quantities of buildings in a 2x2 reactor, which is a good benchmark. At 100%, your 2x2 reactor would produce 720MW of power (180x4) which is significantly more than the typical 480MW.
What I'd like you to consider is that *any* reactor setup will use a whole number of exchangers to consume all the heat generated by the reactors.
1x1 = 5
1x2 = 15
1x3 = 25
2x2 = 40
Even strange setups, such as any 4-reactor setup with one reactor shifted out of the normal 2x2 formation (such as a tetris "T" shape or squiggly) will have a whole number of heat exchangers: 35.