With Space exploration+Krastorio2 it bugs mining Iridite with Big mining drill: "Big mining drill cannot mine the resource" message, breaking ability to progress game (removing Cursed Filter Mining Drill mod fixes problem).
Side note: if you add Electric Mining Drill MK3 (next tier mining drill) via Editor extensions it can mine Iridite

One Possible Solution (Workaround):
Locate your Factorio mods folder and find Cursed-FMD_x.x.x.zip.
Extract the zip file to a folder.
Open info.json with any text editor.
Find the "dependencies" section and add the mods you are using. It should look like this:
"dependencies": ["base", "?space-age", "?bobmining", "?space-exploration", "?Krastorio2"],
Save the file and re-compress the folder back into a .zip file.
Restart Factorio.