Did a reset on all mod settings to defaults before trying to run them together.

All the core Py mods
Alien Life, Alternative Energy, Coal Processing, Fusion, HightTech, Industry, Petroleum, Raw Ores (and assoc. graphics+post-processing)

AAI Industries

Bio Industries

Bob's non-combat
Assembvling machines, Electronics, Logistics, Plates (metals, chemicals, interm.), mining, modules, ores, power, technology

Not running Angels. Also tried w/o AAI to no avail.

Is the required mod list or incompat list perhaps incomplete?

Failed to load mods: pypostprocessing/lib/metas/technology.lua:12: Technology bob-drills-1 does not exist
stack traceback:
[C]: in function 'error'
pypostprocessing/lib/metas/technology.lua:12: in function 'TECHNOLOGY'
.../prototypes/bobs-mods/prototypes/overrides/overrides.lua:15: in main chunk
[C]: in function 'require'
AdminUnknownFixes/prototypes/bobs-mods/Data.lua:1: in main chunk
[C]: in function 'require'
AdminUnknownFixes/data.lua:21: in main chunk

Also tried only enabling mods marked "optional" in your dependencies, and nothing else: instead getting an angel error

Failed to load mods: ...rototypes/angels-mods/prototypes/overrides/overrides.lua:4: attempt to index field 'cellulose-fiber' (a nil value)
stack traceback:
...rototypes/angels-mods/prototypes/overrides/overrides.lua:4: in main chunk
[C]: in function 'require'
AdminUnknownFixes/prototypes/angels-mods/Data.lua:4: in main chunk
[C]: in function 'require'
AdminUnknownFixes/data.lua:15: in main chunk