Glad you like it!
Big patches as you get far from the origin is the idea. Sure, 4.1G is pretty darn big, but that is what you ordered with the settings. Did you mean that to be a criticism?
One of the things about this mod is that it makes exploration more interesting in the late game because there are so few patches, but patches are so valuable once you find them. You can adjust this feature by using the frequency setting. The lowest frequency means patches are the hardest to find but gigantic.
This mod should spawn the same ores that the vanilla map generation system spawns. I put a lot of effort into that. If it is not, please let me know what mod and what ore, and I will look into it.
RSO and PFR both override resource spawning, so in that sense they cannot be compatible. PFR can be turned off on a per-map basis, so you can have it installed but only active on some maps. In that sense, PFR is compatible with other resource generation schemes like vanilla and RSO. However, RSO cannot be turned off and you need to uninstall it to make it stop doing its thing. I looked into it and I do not think there is anything I can do about that.
It does not support ore mixing, if by that you mean ore patches that overlap. There are two reasons for this. 1: with patches this big and valuable, one overlapping patch can ruin a vast quantity of resources. 2: I have never actually enjoyed dealing with overlapping patches. What do you think?
(If you mean mixed ores like Bob's gems, then it does support mixing)
