when i just upgraded factorio from 0.16.25 to 0.16.28, i couldn't start the program without getting this error
failed to load mods:
error while loading item prototype "science-pack-1" (tool):
Prototype "science-pack-1" registered twice
disable all mods / restart / exit
no specific mod was given in that message, but after disabling this mod (by editing the mod-list.json manually), factorio could be started again.
while using factorio 0.16.25 with this mod, i had noticed some strange effects (which wouldn't break the game, but might be connected to the new bug): when using helmod to calculate some production chain, and also on other occasions, the liquid and the science bottles were both shown as the same icon and name and/or the wrong one was shown/used. having the same (bad) prototype for both might be an explanation of those glitches, and some new check in the new factorio finally notices such problems.